🧵 New JAMA Study: Cannabis & Schizophrenia
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A population study of 13.5 million people in Ontario examined how cannabis policy changes relate to schizophrenia diagnoses. Here’s what they found ⬇️
1️⃣ After cannabis became more accessible, the share of new schizophrenia cases linked to cannabis use disorder (CUD) nearly tripled — from ~3.7% to ~10.3%.
2️⃣ People diagnosed with cannabis use disorder were far more likely to later receive a schizophrenia diagnosis compared to those without CUD.
3️⃣ Young men (ages 19–24) had the highest proportion of schizophrenia cases associated with cannabis use disorder.
4️⃣ Overall schizophrenia rates stayed relatively stable, but diagnoses of other psychotic disorders increased after legalization.
5️⃣ Important note:
This study does not say cannabis causes schizophrenia in everyone — but it shows a growing population-level impact of heavy or disordered cannabis use on serious mental illness.
6️⃣ Why this matters 👇
As cannabis becomes more widely used, public health, prevention, and education—especially for young people—are critical.
🔗 Study: JAMA Network Open (2024
https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2829840#google_vignette
Response:
CUD disorder diagnosed being used to skew data here. Relevant counter point: schizophrenia rates have NOT increased post legalization/regulations bankrupting black marketeers.
Like the debunked gateway theory the DEA has officially rejected, this is a reaching argument to claim schizophrenia is caused by cannabis when science clearly shows that isn’t true. If anything, sick people are medicating their illness. Courts have ruled schizophrenics can use cannabis for treating schizophrenia. CBD is being studied for anti-psychotic applications.
The lies and dishonesty around cannabis shall never prevail under rigorous scientific standards, and only discredit scientific integrity. The Moderna Covid shots have been found to, prior to the public being told they were safe, cause death on people.
If science keeps being abused to protect addiction industries and profit motivated pharmaceutical companies humanity is going to suffer unnecessarily.
If not for the emotionality charged around drug policy, millions of lives wouldn’t have been destroyed these past 50 years. What a regrettable state of discourse the world is currently engaged in. Integrity and honesty have all but vanished.
For instance, a study published last year in an imprint of the Journal of the American Medical Association evaluated the relationship between U.S. legalization laws and psychosis rates in more than 63 million privately insured individuals. Researchers described it as the “largest [study] to quantify the association of medical and recreational cannabis policies with rates of psychosis-related health care claims across US states.”
Investigators concluded: “State medical and recreational cannabis policies were not associated with a statistically significant increase in rates of psychosis-related health outcomes.”
They’re not alone in this determination. A just-published consensus study compiled by the National Academies of Sciences, Engineering and Medicine concluded, “There is insufficient evidence of an association between cannabis policy and changes in mental and behavioral health.”
And new data from Canada, published this month in the journal Social Psychiatry and Psychiatric Epidemiology determined that cannabis-related emergency department visits declined among schizophrenia patients following Canada’s adoption of adult-use marijuana legalization.
“Our findings suggest that regulatory measures accompanying legalization could enhance the quality and safety of cannabis products, potentially leading to fewer adverse health outcomes in vulnerable patient populations,” the study’s authors wrote. “Furthermore, our study indicates that legalization and cannabis regulation, in certain contexts, may help reduce acute care utilization in vulnerable patient groups.”
Their findings are particularly relevant because it is well established that those suffering from schizophrenia, psychosis and similar conditions tend to consume cannabis, tobacco and other controlled substances at rates higher than those in the general population. Data also suggests that, in some cases, cannabis use may exacerbate symptoms of psychosis or even trigger a psychotic episode in those predisposed to it. Therefore, regulatory strategies that better educate, target and protect this vulnerable population is critically important.
On the other hand, sensationalizing claims that cannabis use poses significant mental health risks to those not predisposed to such conditions does little to promote either public health or responsible cannabis consumption. In fact, incidences of cannabis-induced psychosis in the general population are rare. When they do occur, they primarily manifest in those with pre-existing mental health conditions, such as bipolar disorder or schizophrenia.
Yet, even in these instances, it often remains unclear the degree to which cannabis use alone is responsible for these outcomes. That’s because marijuana use is one of multiple behaviors commonly associated with psychosis, including consuming alcohol, smoking cigarettes, watching extended hours of television daily and poor diet.
Consequently, little credence should be given to opponents’ allegations that cannabis legalization promotes either unique or significant risks to mental health. Rather, it should be acknowledged that those populations most vulnerable to cannabis-related adverse health events stand to benefit from a regulatory environment that promotes consumer education, product quality control and responsible use.
This op-ed originally appeared in Marijuana Moment.
Additional information is available from NORML’s white paper, Cannabis, Mental Health and Context: The Case For Regulation.
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